Leptin diet: February 2013

5 Day Diet Plan - Intermittent Fasting and Cheating For Faster Weight Loss

The accepted method for faster weight loss has changed. Gone are the days of reducing your calorie intake and keeping it low. This out-of-date method leads to misery and a slow metabolism. Research today is focused on constantly shifting your calorie intake to keep your body confused so it never adapts to your diet. This method keeps your metabolism high and gives you the best and fastest weight loss possible. This article shares a 5 day diet plan that shows you how to use intermittent fasting and cheating days to burn off the fat in record time.

Faster Weight Loss

Leptin

By constantly altering your diet you stay one step ahead of your body and it never has time to adapt to your diet. To do this follow the recommendations below.

5 Day Diet Plan - Intermittent Fasting and Cheating For Faster Weight Loss

Day 1: Start with a Cheat Day. A high calorie day creates the right hormonal conditions inside your body to support rapid weight loss. The key to understanding why this works is to understand that weight loss is highly dependent on hormones. One in particular, leptin, is nicknamed the "anti-starvation" hormone and it is the one most responsible for slowing your metabolism when you fast or severely reduce your calorie intake for more than a few days. When you cheat or overeat you boost your leptin levels and this in turn keeps your metabolism high.

Day 2: Fast or near fast day. On this day keep your calories very low. The conditions are right inside your body for rapid weight loss thanks to Day 1 so use this day to drastically create a calorie deficit. You can further this deficit with exercise on this day.

Day 3: Low calorie day. Though not as severe as Day 2, this day you will keep your calories at a low level. This will vary for different people but generally the low 1,000 calories per day range for women and the mid 1,000 calorie per day range for men.

Day 4: Moderate carbohydrate day: You want to give your body a small energy boost on this day, which can also add back some of the lost glycogen storage (basically carbohydrate storage) into your muscles. Eat a diet with approximately 40% carbohydrates, 30% protein, and 30% fats.

Day 5: Protein only day: This day you will completely deplete your carbohydrate storage again to keep your body confused and also prepare for your next Cheat Day the following day. On this day exercise to further deplete carbohydrate storage.

Repeat this cycle up to 5 times then take a break. Check with your doctor before beginning the diet to be sure it is safe for you and then enjoy the results.

5 Day Diet Plan - Intermittent Fasting and Cheating For Faster Weight Loss

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Irvingia Extract Weight Loss and Side Effects

Irvingia supplement influences at least five key components of fat metabolism. The research details on the impact of Irvingia on weight loss may seem a little technical here. However, they show how unique this herb is in the number of ways that it directs weight loss. This list makes Irvingia unlike any other weight loss supplement. The key effects are as follows.

1) Adiponection is a hormone that is secreted by large fat cells to help support insulin sensitivity and cardiovascular health. Irvingia causes a significant increase in adiponectin levels in overweight people.

Leptin

2) Glycerol-3-phosphate dehydrogenase is an enzyme that converts glucose into triglycerides that then go into storage in fat cells. The result is to make fat cells fatter. Irvingia inhibits the activity of this enzyme, thereby slowing down the growth of fat cells.

Irvingia Extract Weight Loss and Side Effects

3) C-reactive protein blocks the activity of leptin, the master fat hormone, which leads to leptin resistance. Leptin resistance causes fat gain. Overweight people taking Irvingia extract have lower levels of CRP, thereby restoring normal leptin activity and proper fat metabolism.

4) Amylase is an enzyme that breaks down starch to release glucose. Glucose is then absorbed in the digestive tract and taken up as blood sugar. Irvingia inhibits the action of amylase, thereby reducing the number of calories that can be absorbed from eating starch.

5) PPAR-gamma is a key enzyme that regulates the formation of new fat cells and insulin sensitivity. Irvingia inhibits the formation of new fat cells by it influence on PPAR-gamma.

Irvingia Research

The U.S. National Institutes of Health medical database (PubMed) lists 28 research articles that were published on Irvingia since 1980. They involve a wide range of studies on the role of Irvingia in reducing blood sugar in diabetics, relieving pain relief, preventing malaria, in treating bacterial and fungal infections, and even in making Irvingia wine. This variety of effects comes from more than one species of Irvingia and more than one plant part.

The research relevant to the development of this herb as a weight loss supplement concerns an extract of the seeds of one species, Irvingia gabonensis.

Clinical Research On Irvingia Gabonensis Seed Extract

Recent human studies on supplementation using the seed extract of Irvingia gabonensis show significant positive changes after 10 weeks in the following tests: total cholesterol, LDL cholesterol, blood glucose, C-reactive protein, adiponectin, and leptin. These results were based the twice-daily, 150 mg dose, of a proprietary Irvingia gabonensis seed extract.

In addition to the metabolic measurements above, the Irvingia-treated group in this study also lost an average of 12.8 kg (28 lbs) and 6.3 percent body fat. Furthermore, mean waist size in the treatment group dropped just over 16 cm (more than 6 inches) during the study period.

This and other studies shows a remarkably diverse set of physiological effects from Irvingia. Other studies also show its effects on regulating genes that influence the production of hormones and enzymes that control fat metabolism.

Irvingia Side Effects

The main side effect in research studies, and from individual testimonies by people who take Irvingia, is a decrease in appetite. This probably has to do with how the herb reinvigorates leptin activity. Poor leptin activity is associated with hunger and a greater appetite.

Irvingia is also less effective if people eat too much. In other words, it is not a license to overeat.

This herb also seems to have different effects on people who eat a low carb diet. Since the actions of Irvingia are directed at carbohydrate metabolism as it relates to fat cells, complex carbs seem to be important when using this supplement.

Researchers in Cameroon, where Irvingia is a native food source, noticed that long-term consumption of the seeds of this plant is associated with two main side effects:

1) resistance to diabetes; and,
2) resistance to obesity.

These observations are what attracted the attention of medical researchers in the first place. Seeds of Irvingia have been used by indigenous populations as a soup thickener for centuries. People have not suffered any apparent negative side effects from Irvingia even though they typically eat it almost every day of their lives.

Irvingia Extract Weight Loss and Side Effects

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Ten Great Weight Loss Foods That Help You Burn Fat, Build Muscle, and Increase Your Energy

Oxford University and Pennsylvania State University have found that certain foods have fat-burning, muscle-building, or satiety-inducing properties. Here are ten great weight loss foods that help you burn fat, build muscle, and increase your energy. They also help you to control cravings.

1. Raw Fruits and Vegetables

Leptin

Fruits and vegetables high in vitamin C, such as oranges, lemons, pineapples, grapefruit, apples, limes, tomatoes, broccoli, cabbage, celery, carrot, and watermelon liquefy body fat so it can be easily flushed out of your body, according to researchers at Arizona State University.

Ten Great Weight Loss Foods That Help You Burn Fat, Build Muscle, and Increase Your Energy

Pennsylvania State University researchers discovered that people who ate a large apple, approximately 128 calories, 15 minutes before lunch took in 187 fewer calories during lunch than those who didn't snack beforehand. They also reported feeling more satisfied afterward. Apples are loaded with belly-filling fiber, and they require lots of chewing, which can make you think you're eating more than you really are, says study author Julie Obbagy, Ph.D.. Apples contain pectin, a strong appetite suppressant that keeps you satisfied for long periods of time, helping you to avoid overeating so you lose weight.

People who ate half a grapefruit three times a day lost 4 pounds in 12 weeks, even though they hadn't deliberately altered any other part of their diets, according to a recent study from Louisiana State University.

2. Oatmeal

Oatmeal is high in fiber, which helps prevent your body from storing fat and suppresses your appetite. If you eat it about 1 to 2 hours before doing a weight loss workout, it will give you sustained energy, allowing you to work out longer and more intensely which results in faster weight loss. Oatmeal can help to control cholesterol and blood glucose levels. The American Journal of Clinical Nutrition concludes that the use of fiber is an effective and well-tolerated part of a prudent diet for the treatment of high cholesterol. Fiber incorporated into food products is more effective at reducing blood glucose response than a fiber supplement taken separately from the food. Our blood glucose levels can determine how hungry and energetic we feel, and whether we store fat or burn it.

3. Dairy products

Dairy products like low-fat yogurt, cheese, and milk are high in calcium, which breaks down fat cells faster. In a recent study, people who ate low-fat dairy products 3 to 4 times a day lost 70 percent more fat than people on a low-dairy diet. Scientists also believe that foods high in calcium suppress calcitriol, a hormone responsible for making fat cells bigger. Other studies have shown that dairy products contain high-quality proteins that help suppress appetite.

A diet consisting mainly of high calcium foods resulted in an average weight loss of 24.6 pounds in 16 weeks, more than the average weight loss in a year in trials using weight loss drugs like orlistat and sibutramine, according to a 2003 edition of the International Journal of Obesity & Related Metabolic Disorders.

Cheese is an excellent source of casein protein, one of the best muscle-building nutrients you can eat. Danish researchers found that even when men ate 10 ounces of full-fat cheese daily for 3 weeks, their LDL ("bad") cholesterol didn't budge. Researchers at Boston University found that casein protein caused more weight loss and a higher muscle ratio than whey protein. You can eat your cheese and lose weight.

Drinking milk at breakfast can help you eat less at lunch, say Australian scientists. In their study, overweight people who drank about 2 1/2 cups of skim milk in the morning consumed 8.5 percent fewer calories at an all-you-can-eat lunch buffet than people who drank the same amount of fruit juice. Both beverages had an equal number of calories, but the milk contained 25 grams of protein while the fruit juice had virtually no protein and 63 grams of sugar. The high sugar causes your energy to crash after a couple of hours and increases your cravings. It also leads to a depressed emotional state. It's the protein that helps you feel satisfied and nourished throughout the morning.

4. Nuts

Eating a variety of nuts as a snack helps to ward off hunger, and gives you a healthy dose of protein and omega-3 fatty acids, which help you burn fat faster and for men, they help to produce more testosterone. Eat raw and organic nuts instead of roasted and salted to get the full weight loss benefits.

Studies at Loma Linda University in California found that eating about two ounces of nuts a day, five times a week lowered participants' blood cholesterol levels by 12 percent. Walnuts were used, but similar results have been reported with almonds and peanuts. It appears that replacing saturated fat in the diet with the monounsaturated fat in nuts may be the key. It makes sense to eat nuts instead of other fatty, salty snacks.

5. Fish

Eating more fish such as salmon, tuna, and sardines makes your body more sensitive to a fat-burning hormone called leptin, which promotes satiety (Leptin means "thin" in Greek). It controls whether you store the calories you eat as fat or if they are burned for energy.

Because fish are high in protein and omega-3 fatty acids, they make you feel full, stabilize blood sugar, and help to stimulate your metabolism, which helps you lose weight. In a research study from Iceland, dieters who ate salmon felt fuller 2 hours later than those who ate low-fat fish like cod or didn't eat any fish at all. The researchers found that eating foods high in omega-3s increased blood levels of leptin. Don't care for fish? Take a fish oil capsule every day - one that has 500 milligrams of the omega-3s DHA and EPA. It offers the same benefits as salmon.

6. Spices

Add spices to your foods like cayenne peppers, cinnamon, garlic, and hot mustard to increase your fat-burning metabolism by 8 to 20 percent. Spicy foods can reduce your appetite by increasing your body's norepinephrine and epinephrine levels. Dr. Jaya Henry at Oxford University proved that adding 3 grams of chili peppers to meals can significantly increase your fat-burning metabolism. In another British study, spicy mustard made people burn an extra 45 to 75 calories over 3 hours.

Garlic is recognized for its healing powers in ancient times. It is a strong diuretic that can help you flush out excess water weight. Its active component, allicin, may help to prevent weight gain and reduce your levels of insulin, blood pressure, and triglycerides, says T. Rosenthal, lead author for a study published in the American Journal of Hypertension. It is also effective against cancer and heart disease, according to Richard Rivlin, an attending physician at Weill Cornell Medical Center.

7. Resistant starch

Resistant starch is just another kind of dietary fiber, but according to a study done at the University of Colorado, you'll burn 20 to 30 percent more fat by including more foods loaded with resistant starch, such as navy beans, bananas, potatoes, lentils, oatmeal & whole grain breads.

Resistant starch prevents your body from storing too much fat, so you'll never gain weight (and only lose weight). Like other dietary fibers, it leaves you feeling satisfied longer and reduces hunger pangs.

8. Pork Chops

Purdue University researchers found that a 6-ounce serving daily helped people preserve their muscle while losing weight. Australia's Pork CRC study revealed that pork had a more positive effect on PYY, one of the human hormones controlling appetite, than chicken. Initial results found that the pork-based dieters lost weight consisting of body fat while the control group gained weight.

Further research shows that pork chops contain almost five times the selenium per gram of protein as beef, and twice that of chicken. Selenium is an essential mineral that helps the thyroid gland to produce thyroid hormone, which plays a major role in fat metabolism and energy production.

9. Beans

In the National Health and Nutrition Examination Survey, scientists found that people who regularly ate beans were 23 percent less likely to have large waists than those who never ate them. The bean eaters had lower systolic blood-pressure measurements, according to researcher Victor Fulgoni III, PhD.. Legumes are rich in belly-filling fiber as well as potassium, which helps fight hypertension. Eat half a cup of cooked beans 3 or 4 days a week to gain their many benefits and help you lose weight.

10. Eggs

Eating eggs for breakfast can help you control your hunger later in the day. Indiana University scientists determined that dieters who consumed their biggest dose of daily protein at breakfast felt full longer than those who ate more of the nutrient at lunch or dinner. They were less likely to overeat the rest of the day, says study author Heather Leidy, Ph.D.. To ward off hunger before lunch, eat 20 to 30 grams of protein or more for breakfast.

According to research from the Rochester Center for Obesity and Louisiana State University, eating eggs for breakfast could help to limit your calorie intake throughout the rest of the day by more than 400 calories. Eggs are low in calories and high in essential amino acids, selenium, choline, vitamins D, B12, E and A, zinc, and iron.

Implement these ten great weight loss foods that help you burn fat, build muscle, and increase your energy, and you'll live a longer, healthier, and happier life without sacrifice or struggle. Enjoy the new you!

Ten Great Weight Loss Foods That Help You Burn Fat, Build Muscle, and Increase Your Energy

Michael Locklear is a researcher and consultant with 30 years experience, studying health, nutrition, and human behavior. He has been president of the Global Peace Project since 1986, and he administrates the website www.QuickWeightLossTips.info [http://www.quickweightlosstips.info] as part of the Global Peace Project Educational Outreach Program. You can also find him on Facebook.

Negative And Dangerous Side Effects of Excess Blood Sugar

In medical sense, sugar is the amount of glucose that present in the blood. The body of a human normally maintains the level of blood glucose as a part of metabolic homeostasis, and it is the primary source of energy as well. Sugar is not a physiological disorder because it is a part of human organ system. However, it is okay when it is on its normal level, but if the level goes up then many physiological disorders can appear. Excess amount of blood sugar makes the ground for appearing several severe health disorders. According to medical science, high blood sugar shows the way to come numerous negative side effects and these are as follows.

Advanced Glycation End-product (AGEs)

Leptin

Advanced Glycation End-products are the outcome of a chemical reactions chain later than a preliminary glycation reaction. According to the medical professionals, two factors mainly take major part in case of Advanced Glycation End products.

Negative And Dangerous Side Effects of Excess Blood Sugar

The first one is food that we take regularly the first source is the food we eat. If there is high sugar in your food, then it can it may appear. Another source is metabolism through which the carbohydrates are absorbed to affect your blood sugar levels. Nearly all of your blood sugar provides energy that your body requires to perform accurately. Nevertheless, a little amount of your blood sugar is glycated to form the Advanced Glycation End-products. In addition, simple sugars like galactose and fructose go through glycation nearly ten times a higher than the glucose.

Several severe diseases could appear owing to the Advanced Glycation End-products. The diseases are like the Cancer, Alzheimer's disease, Heart disease, Type-II diabetes, Atherosclerosis, High blood pressure, Kidney disorders, Visual impairment, Stroke, Skin disorders.

Depress Immune System

Excess sugar can damage a person's proper immune system, and we all know that devoid of proper immune system a person will be feeble by attacks of many diseases. An active immune system provides fighting power to the organic system to defeat the diseases.

According to medical experts, blood needs vitamin C to maintain a proper immune system. However, if there is excessive sugar in the blood, then there certainly could be a trouble. As the vitamin C and glucose possess same chemical structure, so they fight with each other for entering the blood cells. If there were low sugar, then there would be no trouble, as vitamin C will get the maximum chance to enter into the blood cells. However, if the sugar level is high, then the glucose will have the most cells. In this way, the immune system will be affected, and it will surely be depressed.

If the immune system becomes out of order or feeble, then many serious diseases will surely attack the body. So, in this way excessive sugar in blood can depress the immune system.

Autoimmune diseases

Sugar makes worse autoimmune conditions like asthma, arthritis, and various scleroses. The autoimmune diseases are distinguished by the resistant capability by the own tissues of body. Autoimmune disorders possibly will cause immune responsive cells to show aggression at the inside layer of the joints that is resulting in trigger immune cells or rheumatoid arthritis to attack the insulin making cells of pancreas, and it is known as the islet cells.

An active immune system identifies first, and then attacks, and damages viruses, bacteria, parasites, fungi, and cells cancer or any health destructive agents those are not generally present in the body. An inactive immune system cannot do these all the necessary tasks. Severe diseases like the pancreatitis, Crohn's disease, systemic lupus erythematosus, Hashimoto's thyroiditis, Sjogren's syndrome, and other many more. Allergies and several scleroses are the result of autoimmune diseases. Therefore, the excessive amount of sugar takes a vital part in the autoimmune diseases.

Dental Problems

A human mouth normally includes several kinds of bacteria that attack the tooth. When a person has excessive sugar in blood, the bacteria and germs become more active. The affects on tooth depend upon the amount of the blood sugar a person has in his body. The chances of dental problem depend on how much a person has blood sugar. In normal cases, means when a person is not having high sugar in blood, he or she can be easily cured by removing the affected teeth. However, high sugar patients never can follow such procedure. According to doctors, such course of action will be more harmful for the patients who have excessive sugar in the blood. Moreover, such problem ca eventually turns into malignant or cancer.

Cardiovascular disease

It is well known to all that the sugar is needed in blood, but when it rises over its normal level, several health disorders appear there. The cardio vascular disease is one of those disorders. If a person already has any cardio vascular disease then it could be very dangerous if the person has high blood sugar also. Sugar will help the disease to spread out and react more. If a person does not have any cardio vascular problem then he or she will have a great chance to get it if already carries excess sugar in blood. It mail attacks at the heart, veins, and arteries that provide oxygen to imperative life-sustaining organs of the body such as the heart, brain, and further crucial organs.

Therefore, such kind of disorder can bring in many dangerous diseases to one's body. Finally, the heart or brain may be affected, and so the death may be its horrible result.

Heart Disease

As previously mentioned, excessive sugar in blood can attack at the various part of the cardio vascular system and heart is one of the most important organs of cardio vascular system. If a person has excessive blood sugar, then it can attack any part of cardio vascular system and eventually the heart will be affected. For example, if the sugar attacks veins or arteries, then normally they will stop work, and the hear will not able to keep communication, so it will stop work as well. Thus, the excess sugar can be the cause of severe heart attack.

Faster aging skin

You may come across a fact that the chocolate can damage anyone's skin. However, the chocolate itself is not intrinsically awful for skin, but there possibly will a bit of truth as chocolate comes with excess sugar. It may truly move ahead the aging of a skin, by making the face more wrinkled and less young.

High level of sugar in blood damages the freshness of the skin. Not only, it damages the freshness, but it makes many wrinkles on the face as well. In such case, an affected person look more aged.

Diabetes

The level of sugar in blood is measured according to the presence of glucose in the blood. The glucose is produced as soon as we absorb or digest starchy foods like rice, potatoes, bread and sweet items together with chocolate and sugar. Another source of glucose is liver, as it is also produced there.

There is a hormone that is identified as Insulin, and it carries glucose throughout the bogy cells, where it is made use to make energy. The sugar diabetes patients may have short of insulin, or cannot utilize it, as it should be. It signifies that the excess amount of glucose in the blood carries the symptoms of sugar diabetes.

There are mainly two categories of diabetes, e.g. type 1 and type 2. In case of Diabetes type 1, the body is not capable to make insulin by any means while in case of Diabetes type 2, the body creates excessively small amount of insulin, or may not utilize what it produces efficiently. These both kinds of diabetes show their results in different ways.

High blood pressure

In order to function accurately the glucose is required by the brain. In view of that, it is always suggested not to stay away from glucose completely. However, it is needed to keep away from the sources of glucose. The eating habit of sugar-rich foods, sweets or candy, soft drinks reaches the intestinal tract instantaneously. Then, it causes an immediate reaction for the pancreas to make insulin.

In accordance with the medical experts, too much insulin production takes part in the occurrence of high pressure in blood that is known as high blood pressure. Therefore, the intake of sugar or such kind of food items produces more insulin in body, and it is the major cause of high blood pressure. In view of that fact, it must be mentioned that the sugar is the main source of having high blood pressure.

High blood pressure can take part in several parts of foremost organs like the heart, kidney, vessels, and fetus. It could be very dangerous during the pregnancy time as well.

Yeast Infection

Sugar and yeast infection are too closely related. Sugar and further sugar containing food items are measured to be the major cause of yeast infection. Yeast infection takes place because of excess development of yeast, which is identified as the candida albicans. In fact, the yeast lives in the body in little quantity by default. On the other hand, a number of definite conditions activate the excess growth of the yeast that shows the way to an infection. Such specific infection takes place due to microorganism increases on sugar and further sweet food items, because sugar is one of the major causes of the disorder.

If you are taking high sugar diet, then you must need to deal with such a difficulty. Not only, the sweet food items, but also the over utilization of carbohydrates harm the body similarly. In view of that, you need to stop intake of sweet or carbohydrate containing foods.

Poor Eyesight

People with high level of sugar may have a higher chance of eye problems. However, it never can be sated firmly that a person will have a poor eyesight if he has excess blood sugar. The ADA, which is renowned as the American Diabetic Association, expressed that a good number people with sugar have a bit of chance to have poor eyesight. However, it is recommended to those people who have high sugar, should keep touch with regular eye checkup, as it can become severe any time.

Gastrointestinal disorders

Having excess sugar in the blood possibly will show many health disorders, and gastrointestinal disorder is one of those. Gastrointestinal or the GI track takes vital part in our food absorption, and everyone now knows it. If the foods which we normally intake does not digested properly, then there certainly would be problem in metabolism. Otherwise, excess sugar in blood also affects numerous parts of a human body, and these are very important organs like stomach, duodenum, and pancreas.

Leptin Resistance

Leptin is a most important hormone control the fat mass in case of the vertebrates. The fat tissue makes the leptin to come out and its blood levels are relative to fat mass. So, there will be more fat if there is more secretion of leptin.

As soon as sugar metabolizes in the fat cells, at that time, they make surge from the leptin, and it is found that the sugar take vital part in cases of producing the leptin resistance. Everyone needs to stop taking sugar containing food items to control the right proportion of the leptin in body.

Conclusion:

There is no doubt that excessive sugar in blood will certainly be the cause of numerous difficulties or health disorders. Those all disorders of health even could be a cause of death of human. Therefore, it is suggested to all people to take care of their daily food items and go through the doctors' suggestion to keep always away from high level of sugar in blood.

Negative And Dangerous Side Effects of Excess Blood Sugar

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Bella Vi Afire

Bella Vi Afire slimming herbal capsules are carefully made up using updated scientific procedures. The capsules contain Tea polyphones and Total sponginess. The capsule may decay the traces of triglycerides in the body and organ walls. It is composed to help you get rid of the excess fat cells stored in the body.

The supplement is rich in cellulite factor which helps your body to dissolve the excess fats to excrete through blood. It might also improve the function of intestines by cleaning off the intestinal absorption of toxins and fats.

Leptin

The Bella Vi Afire capsules help in losing weight in three simple steps explained below.

Bella Vi Afire

· In the first step, the botanical lipase and cellulose slow down the regeneration of fat cells, while the supplement removes the excess fat stored in the subcutaneous level. Gradually, the body starts feeling leaner and healthier, while the creases and excess rolls will reduce or go away completely. However, this clearly depends upon the weight you started off with.

· In the second step, the extracts of Tea Polyphenols improve the fat burning process in the body. On an average you will easily lose 4 to 15 pounds bi-weekly, or even 2 to 5 cm in the circumference of the waist.

· In the third step, the supplement will cleanse and dissolve the excess fat cells through blood stream so that they vacate the body through the intestinal tract.

There are various benefits of this supplement, for example, it boosts metabolism, regulates sugar absorption, suppresses appetite, increases fat oxidation, increases energy levels, regulates leptin levels and lowers the fat toxins by thermogenesis.

The ingredients of this supplement are lotus leaf, licorice, magnesium, poria, bitter orange, law pinella, and green tea. You can take two capsules daily before the first meal of the day. The supplement is equally suitable for both men and women. People suffering from serious illness, pregnant and nursing women and children under 18 years of age should avoid taking the supplement.

Bella Vi Afire

The dosage quantity of Bella Vi Afire is 220mg per capsule and there are 60 capsules in each bottle. The shelf life of a bottle is 24 months, whereas you should ensure that the bottle is closed properly and is stored in room temperature. It should not be left to direct exposure to sunlight and extreme heat. To learn more about Bella Vi Products visit us at www.pureedgenutrition.com or call us toll free (888) 417-3613.

The Connection Between Leptin And Obesity

Obesity has become an all too common condition in many of the world's industrialized societies today and is continuing to rise at an alarming rate. In the United States, which currently has the highest rate of obesity of any country in the world, some 60 million adults are classed as being obese and a staggering 9 million adults are considered to be severely or morbidly obese.

Although at first sight it might seem that this is simply the result of changes to our diet and a dramatic drop in the level of physical activity for many Americans in recent years, the reality is that scientific studies into the causes of obesity show that the condition results from a complex combination of factors. One such factor which has come under increasing examination over the past ten years or so is genetics and, in particular, the genes involved in the regulation of leptin within the body.

Leptin

Leptin, which takes its name from the Greek word leptos meaning thin, was discovered in 1994 and is associated with the Ob(lep) gene [Ob - obesity, lep - leptin] which is located on chromosome 7 in human beings. In somewhat simplified terms leptin is a protein hormone produced by fat cells which enters the blood stream and travels to the brain, where a high level of leptin in the blood tells the brain that you have sufficient energy reserves or that your energy reserves are too high and that the body needs to burn off some fat. In essence therefore leptin plays an important role in regulating both appetite and metabolism.

The Connection Between Leptin And Obesity

In obese people levels of leptin found in the blood are normally very high and more than sufficient to suppress the appetite and increase the metabolism. This however does not happen and it is believed that obesity may be the result of a resistance to leptin, in much the same way that people suffering from type 2 diabetes are resistant to insulin.

The problem of course is that the human body is extremely complex and, along with the Ob(lep) gene, there are clearly other genes which play a role in regulating both appetite and metabolism. In addition, leptin does not work in isolation and the manner in which it triggers the brain and the chain of events which it sets into motion is not very well understood at this time.

As things stand today, it is very difficult to say whether or not leptin is truly a factor when it comes to obesity and the scientific literature on the subject does not support any real association between the gene, or genes, which regulate leptin and obesity. Nevertheless, with obesity growing at epidemic rates and our obsession with weight loss fueling an enormous weigh loss industry, the drug companies are now working alongside the scientific community and exploring this whole area in the hope of coming up with a suitable weight loss drug.

The Connection Between Leptin And Obesity

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